Sex- and race-specific associations of bone mineral density with incident heart failure and its subtypes in older adults.

ABSTRACT:

Background

Previous studies have suggested an association between bone mineral density (BMD) and heart failure (HF) risk that may be race-dependent.

Methods

We evaluated the relationship between BMD and incident HF in a cohort of older adults, the Health, Aging, and Body Composition (Health ABC) study (n = 2835), and next performed a pooled analysis involving a second older cohort, the Cardiovascular Health Study (n = 1268). Hip BMD was measured by dual-energy X-ray absorptiometry in both cohorts and spine BMD by computed tomography in a subset from Health ABC.

Results

In Health ABC, lower BMD at the total hip was associated with higher incident HF in Black women after multivariable adjustment. Similar associations were found for BMD at the femoral neck and spine. In

SUBMITTER: Gao H 

PROVIDER: S-EPMC10023291 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature