Semi-quantitative indices of 2-[¹⁸F]FDG PET/CT in assessing cardiovascular and non-cardiovascular manifestations of IgG4-related disease and treatment response.

ABSTRACT:

Background

IgG4-related disease (IgG4-RD) is a heterogeneous autoimmune disorder characterised by inflammatory lesions. Diagnostic imaging, such as 2-[¹⁸F]FDG PET/CT, is critical in evaluation of the disease, especially for potentially lethal cardiovascular manifestations. This retrospective study examines the usefulness of semi-quantitative parameters of 2-[¹⁸F]FDG PET/CT in monitoring IgG4-RD in patients with and without cardiovascular manifestations.

Methods

Patients diagnosed with IgG4-RD who underwent a 2-[¹⁸F]FDG PET/CT scan were identified and classified based on presence or absence of cardiovascular disease. Clinical and laboratory data were extracted and compared to three 2-[¹⁸F]FDG PET/CT semi-quantitative parameters: max

SUBMITTER: Chen M 

PROVIDER: S-EPMC10023819 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature