A clinical trial on anti-diabetic efficacy of submerged culture medium of Ceriporia lacerata mycelium.

ABSTRACT:

Background

Increased glucose level and insulin resistance are major factors in Type 2 diabetes mellitus (T2M), which is chronic and debilitating disease worldwide. Submerged culture medium of Ceriporia lacerata mycelium (CLM) is known to have glucose lowering effects and improving insulin resistance in a mouse model in our previous studies. The main purpose of this clinical trial was to evaluate the functional efficacy and safety of CLM in enrolled participants with impaired fasting blood sugar or mild T2D for 12 weeks.

Methods

A total of 72 participants with impaired fasting blood sugar or mild T2D were participated in a randomized, double-blind, placebo-controlled clinical trial. All participants were randomly assigned into the CLM group or placebo group. Fasting blood glu

SUBMITTER: Kim BH 

PROVIDER: S-EPMC10024018 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature