Role of Tumor Necrosis Factor-α Inhibitors in the Treatment and Occurrence of Acne: A Systematic Review.

ABSTRACT:

Importance

Tumor necrosis factor-α inhibitors (TNFis) approved to treat several inflammatory diseases are sometimes used off label to treat severe forms of acne that are refractory to conventional therapies. However, use of TNFis can also be followed by acne occurrence, suggesting an association between TNFis and acne. Most of the literature on the topic comprises case reports and series that have not been reviewed in a systematic manner.

Objective

To characterize the demographic characteristics, clinical presentations, treatments, and outcomes of patients receiving TNFis to treat acne and patients who develop acne following treatment of other conditions with TNFis.

Evidence review

A systematic literature review was performed and reported in accordance with the Prefer

SUBMITTER: Sandoval AGW 

PROVIDER: S-EPMC10024242 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature