Impact of progesterone on the immune system in women: a systematic literature review.

ABSTRACT:

Purpose

The immune system is influenced by many factors, including female sex hormones. The extent of this influence, however, is not completely understood so far. This systematic literature review aims at giving an overview of the existing concepts on how endogenous progesterone influences the female immune system along the menstrual cycle.

Methods

The inclusion criteria were healthy female subjects in their reproductive age with a regular menstrual cycle. The exclusion criteria were exogenous progesterone, animal models, nonhealthy study populations and pregnancy. This led to 18 papers covered in this review. The search was performed using the databases EMBASE, Ovid MEDLINE and Epub, and the last search was conducted on September 18, 2020. Our findings were analyzed in fou

SUBMITTER: Zwahlen M 

PROVIDER: S-EPMC10024519 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature