Language impairment in the genetic forms of behavioural variant frontotemporal dementia.

ABSTRACT:

Background

Behavioural variant fronto-temporal dementia (bvFTD) is characterised by a progressive change in personality in association with atrophy of the frontal and temporal lobes. Whilst language impairment has been described in people with bvFTD, little is currently known about the extent or type of linguistic difficulties that occur, particularly in the genetic forms.

Methods

Participants with genetic bvFTD along with healthy controls were recruited from the international multicentre Genetic FTD Initiative (GENFI). Linguistic symptoms were assessed using items from the Progressive Aphasia Severity Scale (PASS). Additionally, participants undertook the Boston Naming Test (BNT), modified Camel and Cactus Test (mCCT) and a category fluency test. Participants underwent a 3T

SUBMITTER: Samra K 

PROVIDER: S-EPMC10025186 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature