DBS in tremor with dystonia: VIM, GPi or both? A review of the literature and considerations from a single-center experience.

ABSTRACT:

Background

Deep brain stimulation (DBS) is an established treatment for dystonia and tremor. However, there is no consensus about the best surgical targeting strategy in patients with concomitant tremor and dystonia. Both the thalamic ventral intermediate nucleus (VIM) and the globus pallidus pars interna (GPi) have been proposed as targets. Few cases using them together in a double-target approach have also been reported.

Methods

We reviewed the literature on this topic, summarizing results of different target choices. Additionally, we retrospectively report a case series of nine patients with sporadic dystonia and severe tremor treated with a double-target strategy at our center. Outcome measures were the Burke-Fahn-Marsden Dystonia Rating Scale (BFM) and Eq-5d scale.

R

SUBMITTER: Paoli D 

PROVIDER: S-EPMC10025201 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature