Intrasession Repeatability of OCT Angiography Parameters in Neurodegenerative Disease.

ABSTRACT:

Purpose

To assess the intrasession repeatability of macular OCT angiography (OCTA) parameters in Alzheimer's disease (AD), mild cognitive impairment (MCI), Parkinson's disease (PD), and normal cognition (NC).

Design

Cross sectional study.

Subjects

Patients with a clinical diagnosis of AD, PD, MCI, or NC were imaged. Images with poor quality and of those with diabetes mellitus, glaucoma, or vitreoretinal disease were excluded from analysis.

Methods intervention or testing

All participants were imaged using the Zeiss Cirrus HD-5000 with AngioPlex (Carl Zeiss Meditec, Software Version 11.0.0.29946) and repeat OCTA images were obtained for both eyes. Perfusion density (PFD), vessel density (VD), and Foveal avascular zone (FAZ) area were measured from 3 × 3 mm and 6

SUBMITTER: Akrobetu DY 

PROVIDER: S-EPMC10025280 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature