Probiotics to prevent necrotizing enterocolitis in very low birth weight infants: A network meta-analysis.

ABSTRACT:

Objective

This study aims to review the evidence for the optimal regimen of probiotics for the prevention of necrotizing enterocolitis (NEC) in very low birth weight infants.

Design

Through searching PubMed, EMBASE, Cochrane Library, and Web of Science till September 30, 2022, only randomized controlled trials were included to evaluate the optimal regimen of probiotics for the prevention of NEC in very low birth weight infants. The methodological quality of the included studies was assessed by the Cochrane risk of bias assessment tool (RoB 2), and the collected data were analyzed accordingly using Stata software.

Results

Twenty-seven RCTs were included, and the total sample size used in the study was 529. The results of the network meta-analysis showed that Bovine lac

SUBMITTER: Zhou KZ 

PROVIDER: S-EPMC10025406 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature