The causal relationship between COVID-19 and increased intraocular pressure: A bidirectional two-sample Mendelian randomization study.

ABSTRACT:

Background

Coronavirus disease 2019 (COVID-19) has brought great challenges to the global public health system and huge economic burdens to society, the causal effect of COVID-19 and intraocular pressure was blank.

Objective

This study aimed to explore the causal association between coronavirus disease (COVID-19) susceptibility, severity and criticality and intraocular pressure (IOP) by bidirectional Mendelian randomization (MR) analysis.

Materials and methods

Genetic associations with COVID-19 susceptibility, severity and criticality were obtained from the COVID-19 Host Genetics Initiative. Genetic associations with IOP were obtained from GWAS summary data. The standard inverse variance weighted (IVW) method was used in the primary assessment of this causality. Other

SUBMITTER: Lin Y 

PROVIDER: S-EPMC10025528 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature