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The effect of depressive symptoms on disability-free survival in healthy older adults: A prospective cohort study.


ABSTRACT:

Background

Gerontology and ageing research are increasingly focussing on healthy life span (healthspan), the period of life lived free of serious disease and disability. Late-life depression (LLD) is believed to impact adversely on physical health. However, no studies have examined its effect on healthspan. This study investigated the effect of LLD and subthreshold depression on disability-free survival, a widely accepted measure of healthspan.

Methods

This prospective cohort study used data from the ASPirin in Reducing Events in the Elderly study. Participants were aged ≥70 years (or ≥65 years for African-American and Hispanic participants) and free of dementia, physical disability and cardiovascular disease. Depressive symptoms were measured using the 10-item Centre for Ep

SUBMITTER: Roebuck G 

PROVIDER: S-EPMC10026010 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature