Research trends and hotspots of mesenchymal stromal cells in intervertebral disc degeneration: a scientometric analysis.

ABSTRACT: Mesenchymal stromal cells (MSCs) are important potential candidates for regenerative therapy for intervertebral disc degeneration (IDD). This scientometric study aimed to summarize the main research trends, identify current research hotspots, and measure the networks of the contributors and their scientific productivity. A total of 1102 publications regarding MSC in IDD were recognized from January 2000 to April 2022. The number of records every year followed an overall uptrend with fluctuations. The main trend of research demonstrated the practice of gradually applying MSC-based therapy to IDD with the assistance of advances in biomaterials and IDD pathology. A recent focus on MSC-derived exosomes and notochordal cells was detected. The basic studies in this field were mainly contributed

SUBMITTER: Yao M 

PROVIDER: S-EPMC10026060 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature