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Evaluating the impact of early identification of asymptomatic brain metastases in metastatic renal cell carcinoma.


ABSTRACT:

Background

Brain metastases (BM) in metastatic renal cell carcinoma (mRCC) have been reported to be present in up to 25% of patients diagnosed with mRCC. There is limited published literature evaluating the role of routine intra-cranial imaging for the screening of asymptomatic BM in mRCC.

Aims

To evaluate the potential utility of routine intra-cranial imaging, a retrospective cohort study was conducted to characterize the outcomes of mRCC patients who presented with asymptomatic BM, as compared to symptomatic BM.

Methods and results

The Canadian Kidney Cancer Information System (CKCis) database was used to identify mRCC patients diagnosed with BM. This cohort was divided into two groups based on the presence or absence of BM symptoms. Details regarding patient demogr

SUBMITTER: Parmar A 

PROVIDER: S-EPMC10026314 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature