Blood pressure and dementia risk by physical frailty in the elderly: a nationwide cohort study.

ABSTRACT:

Background

Midlife hypertension has been recognized as a modifiable risk factor for dementia, but association between blood pressure (BP) in late life and dementia has been inconclusive. In addition, few studies have investigated effects of BP control on dementia incidence in the frail elderly. Thus, this study aimed to investigate the association of BP and dementia incidence with concomitant consideration of physical frailty in the young elderly population.

Methods

Using the Korean National Health Information Database, we identified 804,024 subjects without history of dementia at age 66. Dementia diagnosis was defined with prescription records of anti-dementia drugs and dementia-related diagnostic codes. Physical frailty was measured using the Timed Up and Go test. Associat

SUBMITTER: Cho MH 

PROVIDER: S-EPMC10026431 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature