Investigator-Determined Categories for Fever of Unknown Origin (FUO) Compared With International Classification of Diseases–10 Classification of Illness: A Systematic Review and Meta-analysis With a Proposal for Revised FUO Classification

ABSTRACT: Abstract

Background

Classifying fever of unknown origin (FUO) into categorical etiologies (ie, infections, noninfectious inflammatory, oncologic, miscellaneous, and undiagnosed disorders) remains unstandardized and subject to discrepancies. As some disease classifications change, a systematic review of studies would help physicians anticipate the frequency of illness types they may encounter that could influence care.

Methods

We systematically reviewed prospective FUO studies published across the Medline (PubMed), Embase, Scopus, and Web of Science databases from January 1, 1997, to July 31, 2022. We performed a meta-analysis to estimate associated pooled proportions between the investigator-determined choice of disease category and those determined by the International C

SUBMITTER:  

PROVIDER: S-EPMC10026547 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature