Is Balneotherapy Protective Against Oxidative Stress? A Pilot Study.

ABSTRACT:

Background/aim

This study aimed to research the effects of Harkány healing water on oxidative stress. The study was performed in a randomized, placebo-controlled, double-blind setup.

Patients and methods

Twenty patients with psoriasis who underwent a 3-week-long inward balneotherapy-based rehabilitation were enrolled. Psoriasis Area and Severity Index (PASI) score and Malondialdehyde (MDA) - a marker of oxidative stress - were determined, on admission and before discharge. Patients were treated with dithranol.

Results

The mean PASI score - determined on admission and before discharge - decreased significantly after the 3-week-long rehabilitation 8.17 vs. 3.51 (p<0.001). The baseline MDA value of patients with psoriasis was significantly higher compared to controls (3.

SUBMITTER: Szenczi A 

PROVIDER: S-EPMC10026676 | biostudies-literature | 2023 Mar-Apr

REPOSITORIES: biostudies-literature