Mobile health lifestyle intervention program leads to clinically significant loss of body weight in patients with NASH.

ABSTRACT:

Background aims

Lifestyle intervention remains the foundation of clinical care for patients with NASH; however, most patients are unsuccessful in enacting sustained behavioral change. There remains a clear unmet need to develop lifestyle intervention programs to support weight loss. Mobile health (mHealth) programs offer promise to address this need, yet their efficacy remains unexplored.

Approach results

We conducted a 16-week randomized controlled clinical trial involving adults with NASH. Patients were randomly assigned (1:1 ratio) to receive Noom Weight (NW), a mHealth lifestyle intervention program, or standard clinical care. The primary end point was a change in body weight. Secondary end points included feasibility (weekly app engagement), acceptability (>50% approach

SUBMITTER: Stine JG 

PROVIDER: S-EPMC10027041 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature