A deeper insight into the sialome of male and female Culex quinquefasciatus mosquitoes.

ABSTRACT:

Introduction

During evolution, blood-feeding arthropods developed a complex salivary mixture that can interfere with host haemostatic and immune response, favoring blood acquisition and pathogen transmission. Therefore, a survey of the salivary gland contents can lead to the identification of molecules with potent pharmacological activity in addition to increase our understanding of the molecular mechanisms underlying the hematophagic behaviour of arthropods. The southern house mosquito, Culex quinquefasciatus, is a vector of several pathogenic agents, including viruses and filarial parasites that can affect humans and wild animals.

Results

Previously, a Sanger-based transcriptome of the salivary glands (sialome) of adult C. quinquefasciatus females was published based on th

SUBMITTER: Lu S 

PROVIDER: S-EPMC10027276 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature