Meta-analysis of the space flight and microgravity response of the Arabidopsis plant transcriptome.

ABSTRACT: Spaceflight presents a multifaceted environment for plants, combining the effects on growth of many stressors and factors including altered gravity, the influence of experiment hardware, and increased radiation exposure. To help understand the plant response to this complex suite of factors this study compared transcriptomic analysis of 15 Arabidopsis thaliana spaceflight experiments deposited in the National Aeronautics and Space Administration's GeneLab data repository. These data were reanalyzed for genes showing significant differential expression in spaceflight versus ground controls using a single common computational pipeline for either the microarray or the RNA-seq datasets. Such a standardized approach to analysis should greatly increase the robustness of comparisons made between

SUBMITTER: Barker R 

PROVIDER: S-EPMC10027818 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature