Evaluation of transcutaneous near-infrared spectroscopy for early detection of cardiac arrest in an animal model.

ABSTRACT: Sudden cardiac arrest (SCA) is a leading cause of mortality worldwide. The SCA-to-resuscitation interval is a key determinant of patient outcomes, highlighting the clinical need for reliable and timely detection of SCA. Near-infrared spectroscopy (NIRS), a non-invasive optical technique, may have utility for this application. We investigated transcutaneous NIRS as a method to detect pentobarbital-induced changes during cardiac arrest in eight Yucatan miniature pigs. NIRS measurements during cardiac arrest were compared to invasively acquired carotid blood pressure and partial oxygen pressure (PO₂) of spinal cord tissues. We observed statistically significant decreases in mean arterial pressure (MAP) 64.68 mmHg ± 13.08, p < 0.0001), spinal cord PO₂ (38.16 mmHg ± 20.04,

SUBMITTER: Raschdorf K 

PROVIDER: S-EPMC10027843 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature