Alpha peak activity in resting-state EEG is associated with depressive score.

ABSTRACT:

Introduction

Depression is a serious psychiatric disorder characterized by prolonged sadness, loss of interest or pleasure. The dominant alpha peak activity in resting-state EEG is suggested to be an intrinsic neural marker for diagnosis of mental disorders.

Methods

To investigate an association between alpha peak activity and depression severity, the present study recorded resting-state EEG (EGI 128 channels, off-line average reference, source reconstruction by a distributed inverse method with the sLORETA normalization, parcellation of 68 Desikan-Killiany regions) from 155 patients with depression (42 males, mean age 35 years) and acquired patients' scores of Self-Rating Depression Scales. We measured both the alpha peak amplitude that is more related to synchronous neural

SUBMITTER: Zhou P 

PROVIDER: S-EPMC10027937 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature