Disrupted interhemispheric coordination of sensory-motor networks and insula in major depressive disorder.

ABSTRACT:

Objective

Prior researches have identified distinct differences in neuroimaging characteristics between healthy controls (HCs) and patients with major depressive disorder (MDD). However, the correlations between homotopic connectivity and clinical characteristics in patients with MDD have yet to be fully understood. The present study aimed to investigate common and unique patterns of homotopic connectivity and their relationships with clinical characteristics in patients with MDD.

Methods

We recruited 42 patients diagnosed with MDD and 42 HCs. We collected a range of clinical variables, as well as exploratory eye movement (EEM), event-related potentials (ERPs) and resting-state functional magnetic resonance imaging (rs-fMRI) data. The data were analyzed using correlation ana

SUBMITTER: Zhang C 

PROVIDER: S-EPMC10028102 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature