Clinical results of active surveillance for extra-abdominal desmoid-type fibromatosis.

ABSTRACT:

Background

The treatment of choice for desmoid-type fibromatosis (DF) has been changed to active surveillance (AS). However, few studies have reported clinical outcomes of AS modality in Asian countries. This study aimed to clarify the significance of AS as a DF treatment modality.

Methods

A total of 168 lesions from 162 patients with extra-abdominal DF were included. The mean age at diagnosis was 39 years (1-88 years), and the median maximum tumor diameter at the first visit was 64.1 mm (13.2-255.8 mm). The clinical outcomes of AS and the risk factors requiring active treatment (AT) (defined as an event) from AS modality were investigated.

Results

Of the 168 lesions, 94 (56%) were able to continue AS, with a 5-year event-free survival of 54.8%. Of the 68 lesions with

SUBMITTER: Sakai T 

PROVIDER: S-EPMC10028109 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature