Dataset Information

Creating affiliations, learning, and mindfulness for in vitro fertilization patients (CALM IVF): a clinical trial.

ABSTRACT:

Objective

Determine if group psychoeducational support can improve in vitro fertilization (IVF) patients' quality of life (QoL).

Design

Randomized controlled trial (NCT04048772).

Setting

University-affiliated IVF clinic.

Patients

Women (n = 76) and male partners undergoing initial autologous IVF cycle from August 2019, to December 2020.

Interventions

Couples were assigned to groups based on projected oocyte retrieval date. Groups were randomly assigned to the control or intervention arm. Clinic closures because of the COVID-19 pandemic delayed treatment for a portion of participants. Groups were conducted in person before and virtually during the pandemic.

Main outcome measures

The primary outcome was a change in fertility quality of life (FertiQoL) from baseline to 3 days after retrieval. Secondary outcomes were changes in depression (Patient Health Questionnaire 9), anxiety (Generalized Anxiety Disorder 7), resilience (Connor-Davidson Resilience scale), IVF knowledge scores, and the likelihood of return to treatment.

Results

Knowledge scores among women in Creating Affiliations, Learning, and Mindfulness (CALM) for IVF groups significantly increased compared with control (mean difference 13.19 [3.53 - 22.84]) before the pandemic. During the pandemic, women in CALM IVF had significant improvement in the social FertiQoL score compared with controls (10.42 [1.79 - 19.04]). Compared with controls, male CALM IVF participants had significantly greater improvement in total FertiQoL (mean difference 6.68 [0.39 - 12.98]), treatment FertiQoL (8.26 [0.69 - 15.82]), and resilience (Connor-Davidson 1.13 [0.54 - 1.72]). Immediate return to care did not significantly differ between arms.

Conclusions

For women undergoing IVF, group psychoeducational programs can improve IVF knowledge and social QoL during a pandemic. Participation in a group psychoeducational program can improve QoL and resilience in IVF dyad male partners.

Clinical trial registration number

Trial registration NCT04048772.

SUBMITTER: Whynott RM

PROVIDER: S-EPMC10028477 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Creating affiliations, learning, and mindfulness for in vitro fertilization patients (CALM IVF): a clinical trial.

Whynott Rachel M RM Summers Karen M KM Mejia Rachel B RB Segre Lisa S LS Ryan Ginny G Pawlak Stacey A SA

F&S reports 20230107 1

<h4>Objective</h4>Determine if group psychoeducational support can improve in vitro fertilization (IVF) patients' quality of life (QoL).<h4>Design</h4>Randomized controlled trial (NCT04048772).<h4>Setting</h4>University-affiliated IVF clinic.<h4>Patients</h4>Women (n = 76) and male partners undergoing initial autologous IVF cycle from August 2019, to December 2020.<h4>Interventions</h4>Couples were assigned to groups based on projected oocyte retrieval date. Groups were randomly assigned to the ...[more]

PMID: 36959953

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Dataset Information

Creating affiliations, learning, and mindfulness for in vitro fertilization patients (CALM IVF): a clinical trial.

Objective

Design

Setting

Patients

Interventions

Main outcome measures

Results

Conclusions

Clinical trial registration number

Publications

Creating affiliations, learning, and mindfulness for in vitro fertilization patients (CALM IVF): a clinical trial.

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