Estimating the share of SARS-CoV-2-immunologically naive individuals in Germany up to June 2022.

ABSTRACT: After the winter of 2021/2022, the coronavirus disease 2019 (COVID-19) pandemic had reached a phase where a considerable number of people in Germany have been either infected with a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant, vaccinated or both, the full extent of which was difficult to estimate, however, because infection counts suffer from under-reporting, and the overlap between the vaccinated and recovered subpopulations is unknown. Yet, reliable estimates regarding population-wide susceptibility were of considerable interest: Since both previous infection and vaccination reduce the risk of severe disease, a low share of immunologically naïve individuals lowers the probability of further severe outbreaks, given that emerging variants do not escape the acquired

SUBMITTER: Maier BF 

PROVIDER: S-EPMC10028997 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature