Antibodies against Periodontal Microorganisms and Cognition in Older Adults.

ABSTRACT:

Introduction

Markers of poor oral health are associated with impaired cognition and higher risk of Alzheimer disease (AD) and thus may help predict AD.

Objectives

The aim of this study was to evaluate the cross-sectional association between empirically derived groups of 19 IgG antibodies against periodontal microorganisms and cognition in middle-aged and older adults.

Methods

The study population consisted of participants of the third National Health and Nutrition Examination Survey (NHANES III) (1988 to 1994), who were 60 y and older, among whom cognition and IgG antibodies against 19 periodontal microorganisms were measured (N = 5,162).

Results

In multivariable quantile regression analyses, the Orange-Red (Prevotella melaninogenica, Prevotella intermed

SUBMITTER: Merchant AT 

PROVIDER: S-EPMC10029137 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature