Minimally invasive versus open esophagectomy after neoadjuvant therapy for esophageal cancer: a meta-analysis.

ABSTRACT:

Objectives

Neoadjuvant therapy and minimally invasive esophagectomy (MIE) are widely used in the comprehensive treatment of esophageal cancer. This study aimed to investigate the advantages of MIE for esophageal cancer after neoadjuvant therapy.

Methods

Published clinical studies were reviewed and survival data and safety data were extracted. We compared the long-term survival and safety of MIE versus open esophagectomy after neoadjuvant surgery in a series of meta-analyses.

Results

6 retrospective studies were included. Overall, MIE could significantly improve the overall survival of patients with esophageal cancer after neoadjuvant therapy compared with open esophagectomy [hazard ratio (HR) = 0.86, 95% confidence interval (CI) (0.75, 0.98)]. Compared with open esoph

SUBMITTER: Jin Z 

PROVIDER: S-EPMC10029261 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature