Differences Between Ruptured Aneurysms With and Without Blebs: Mechanistic Implications.

ABSTRACT:

Purpose

Blebs are known risk factors for intracranial aneurysm (IA) rupture. We analyzed differences between IAs that ruptured with blebs and those that ruptured without developing blebs to identify distinguishing characteristics among them and suggest possible mechanistic implications.

Methods

Using image-based models, 25 hemodynamic and geometric parameters were compared between ruptured IAs with and without blebs (n = 673), stratified by location. Hemodynamic and geometric differences between bifurcation and sidewall aneurysms and for aneurysms at five locations were also analyzed.

Results

Ruptured aneurysms harboring blebs were exposed to higher flow conditions than aneurysms that ruptured without developing blebs, and this was consistent across locations. Bifurca

SUBMITTER: Salimi Ashkezari SF 

PROVIDER: S-EPMC10029732 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature