Blood cell counts can predict adverse events of immune checkpoint inhibitors: A systematic review and meta-analysis.

ABSTRACT:

Background

Cancer is concerning owing to its high mortality rate. Consequently, methods of prolonging the life of patients with cancer have become the primary focus of attention research. In recent years, immune checkpoint inhibitors (ICIs) have achieved good clinical efficacy as antitumor drugs; however, their severe adverse effects have made their use challenging. In order to clarify the predictors of adverse effects, scientists have conducted a series of studies. Blood counts can potentially monitor risk factors associated with the occurrence of immune-related adverse events (irAEs). Herein, a meta-analysis was performed to clarify further the guiding significance of blood counts in the clinical setting.

Methods

Studies that satisfied the inclusion criteria were obtained

SUBMITTER: Zhou J 

PROVIDER: S-EPMC10029759 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature