COVID-19 and its continuing burden after 12 months: a longitudinal observational prospective multicentre trial.

ABSTRACT:

Background

Recovery trajectories from coronavirus disease 2019 (COVID-19) call for longitudinal investigation. We aimed to characterise the kinetics and status of clinical, cardiopulmonary and mental health recovery up to 1 year following COVID-19.

Methods

Clinical evaluation, lung function testing (LFT), chest computed tomography (CT) and transthoracic echocardiography were conducted at 2, 3, 6 and 12 months after disease onset. Submaximal exercise capacity, mental health status and quality of life were assessed at 12 months. Recovery kinetics and patterns were investigated by mixed-effect logistic modelling, correlation and clustering analyses. Risk of persistent symptoms and cardiopulmonary abnormalities at the 1-year follow-up were modelled by logistic regression.

Fin

SUBMITTER: Sahanic S 

PROVIDER: S-EPMC10030059 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature