Dataset Information

Patient-reported burden and overall impact of dry eye disease across eight European countries: a cross-sectional web-based survey.

ABSTRACT:

Objective

Dry eye disease (DED) is a multifactorial disease involving the tears and ocular surface. It impacts a patient's quality of life (QoL) and ability to perform daily activities. This study assessed the burden of self-reported DED among adults in eight European countries.

Design

Online cross-sectional survey.

Setting

General population in France, Italy, Germany, Greece, the Netherlands, Portugal, Spain and Sweden.

Participants

Adults aged ≥18 years with (n=6084) and without (n=6161) self-reported DED were recruited via emails and screened.

Main outcome measures

All participants completed National Eye Institute Visual Function Questionnaire-25 (NEI-VFQ-25) and EuroQol-5 Dimension-5 Level Questionnaire (EQ-5D-5L). All DED participants completed the Eye Dryness Score (EDS) Visual Analogue Scale, and Ocular Comfort Index and Work Productivity and Activity Impairment Questionnaire: Specific Health Problem questionnaires. In addition, half of the respondents with DED completed Survey A (Impact of Dry Eye on Everyday Life) and the other half completed Survey B (Standard Patient Evaluation of Eye Dryness Questionnaire) and Dry Eye Questionnaire-5.

Results

Participants with self-reported DED had lower functional vision and lower overall health status than participants without self-reported DED as measured by the NEI-VFQ and EQ-5D-5L, respectively.Increasing self-reported DED severity as measured by the EDS was shown to correspond with worse symptom severity/frequency, lower functional vision, higher impact on work productivity, daily activities and QoL.

Conclusion

This study showed that patients' reported burden of self-reported DED was similar across the eight European countries. Those with self-reported DED reported lower health status and functional vision compared to those without self-reported DED and these parameters worsen with increasing disease severity.

SUBMITTER: Boboridis KG

PROVIDER: S-EPMC10030789 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Patient-reported burden and overall impact of dry eye disease across eight European countries: a cross-sectional web-based survey.

Boboridis Kostas G KG Messmer Elisabeth M EM Benítez-Del-Castillo José J Meunier Juliette J Sloesen Brigitte B O'Brien Paul P Quadrado Maria Joao MJ Rolando Maurizio M Labetoulle Marc M

BMJ open 20230317 3

<h4>Objective</h4>Dry eye disease (DED) is a multifactorial disease involving the tears and ocular surface. It impacts a patient's quality of life (QoL) and ability to perform daily activities. This study assessed the burden of self-reported DED among adults in eight European countries.<h4>Design</h4>Online cross-sectional survey.<h4>Setting</h4>General population in France, Italy, Germany, Greece, the Netherlands, Portugal, Spain and Sweden.<h4>Participants</h4>Adults aged ≥18 years with (n=608 ...[more]

PMID: 36931668

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Dataset Information

Patient-reported burden and overall impact of dry eye disease across eight European countries: a cross-sectional web-based survey.

Objective

Design

Setting

Participants

Main outcome measures

Results

Conclusion

Publications

Patient-reported burden and overall impact of dry eye disease across eight European countries: a cross-sectional web-based survey.

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