Associations between multi-method latent factors of puberty and brain structure in adolescent girls.

ABSTRACT: Pubertal processes are associated with structural brain development, but studies have produced inconsistent findings that may relate to different measurements of puberty. Measuring both hormones and physical characteristics is important for capturing variation in neurobiological development. The current study explored associations between cortical thickness and latent factors from multi-method pubertal data in 174 early adolescent girls aged 10-13 years in the Transitions in Adolescent Girls (TAG) Study. Our multi-method approach used self-reported physical characteristics and hormone levels (dehydroepiandrosterone (DHEA), testosterone (T), and estradiol (E2) from saliva) to estimate an overall pubertal factor and for each process of adrenarche and gonadarche. There were negative associati

SUBMITTER: Byrne ML 

PROVIDER: S-EPMC10031110 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature