The persistence and stabilization of auxiliary genes in the human skin virome.

ABSTRACT:

Background

The human skin contains a diverse microbiome that provides protective functions against environmental pathogens. Studies have demonstrated that bacteriophages modulate bacterial community composition and facilitate the transfer of host-specific genes, potentially influencing host cellular functions. However, little is known about the human skin virome and its role in human health. Especially, how viral-host relationships influence skin microbiome structure and function is poorly understood.

Results

Population dynamics and genetic diversity of bacteriophage communities in viral metagenomic data collected from three anatomical skin locations from 60 subjects at five different time points revealed that cutaneous bacteriophage populations are mainly composed of tailed

SUBMITTER: Graham EH 

PROVIDER: S-EPMC10031188 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature