Refractory wounds induced by normal-renal calciphylaxis: An under-recognised calcific arteriolopathy.

ABSTRACT:

Background

Normal-renal calciphylaxis (NRC) is a devastating calcific vasculopathy characterised by refractory wounds. It is more likely to be misdiagnosed because of the absence of renal insufficiency. Failure to effectively control may lead to rapid deterioration and ultimately death. However, current knowledge of it is still inadequate.

Objectives

To provide a relatively comprehensive review of NRC.

Methods

Nine electronic medical databases including PubMed, Web of Science, Embase, the Cochrane Library and so on were searched from inception to April 1, 2022. Articles in which calciphylaxis was diagnosed in patients with normal renal function were included.

Results

Totally 140 articles were retrieved with 187 patients (median age, 62 years [IQR, 49.63 ~ 75.70

SUBMITTER: Wu J 

PROVIDER: S-EPMC10031205 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature