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Liquid ozone therapies for the treatment of epithelial wounds: A systematic review and meta-analysis.


ABSTRACT: Ozonated water and ozonated oils are emerging as potential therapies for wound care, but their efficacy has not been appropriately evaluated. The aim of this systematic review and meta-analysis was to evaluate the therapeutic potential of topical ozone in the treatment of mammalian wounds. A structured search of five scientific databases returned a total of 390 unique studies. Of these, 22 studies were included in this review. Four studies provided enough data to be included in a meta-analysis evaluating the time to complete wound healing. All studies were randomised controlled trials of humans or other mammalian animals that reported clinical signs of wound healing. Each study was critically analysed by a six-point assessment of the risk of bias. Wounds treated with topical ozone had a gr

SUBMITTER: Romary DJ 

PROVIDER: S-EPMC10031250 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature