Keeping the Death Protein in Check.

ABSTRACT: Gasdermin D is an executioner of inflammatory cell death. In this issue, Liu et al. report the crystal structures of full-length human and mouse gasdermin D, which contributes to our understanding of gasdermin D autoinhibition and activation and will inform the future development of therapeutics targeting gasdermin D.

SUBMITTER: Wang L 

PROVIDER: S-EPMC10031939 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature