Subclinical thyroid dysfunction and chronic kidney disease: a nationwide population-based study.

ABSTRACT:

Background

Chronic kidney disease (CKD) has a significant impact on global health. Studies have shown that subclinical thyroid dysfunction may be related to CKD, but the association between subclinical thyroid dysfunction and CKD in the general population is unclear. We aimed to evaluate the risk of CKD according to thyroid function status in a large cohort.

Methods

We analyzed data from a nationwide, population-based, cross-sectional survey (KNHANES VI). A total of 3,257 participants aged ≥ 19 years who underwent thyroid and kidney function assessments were included in this study. CKD was defined as an estimated glomerular filtration rate < 60 mL/min/1.73 m² and/or urine albumin-creatinine ratio ≥ 30 mg/g. The risk of CKD according to thyroid function status was

SUBMITTER: Kim HJ 

PROVIDER: S-EPMC10031940 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature