Maternal weight, gut microbiota, and the association with early childhood behavior: the PREOBE follow-up study.

ABSTRACT:

Background and aim

Maternal overweight and breastfeeding seem to have a significant impact on the gut microbiota colonization process, which co-occurs simultaneously with brain development and the establishment of the "microbiota-gut-brain axis", which potentially may affect behavior later in life. This study aimed to examine the influence of maternal overweight, obesity and/or gestational diabetes on the offspring behavior at 3.5 years of age and its association with the gut microbiota already established at 18 months of life.

Methods

156 children born to overweight (OV, n = 45), obese (OB, n = 40) and normoweight (NW, n = 71) pregnant women participating in the PREOBE study were included in the current analysis. Stool samples were collected at 18 months of life and gut mic

SUBMITTER: Nieto-Ruiz A 

PROVIDER: S-EPMC10031971 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature