CT-derived fractional flow reserve for prediction of major adverse cardiovascular events in diabetic patients.

ABSTRACT:

Objectives

To investigate the prognostic value of computed tomography fractional flow reserve (CT-FFR) in patients with diabetes and to establish a risk stratification model for major adverse cardiac event (MACE).

Methods

Diabetic patients with intermediate pre-test probability of coronary artery disease were prospectively enrolled. All patients were referred for coronary computed tomography angiography and followed up for at least 2 years. In the training cohort comprising of 957 patients, two models were developed: model1 with the inclusion of clinical and conventional imaging parameters, model2 incorporating the above parameters + CT-FFR. An internal validation cohort comprising 411 patients and an independent external test cohort of 429 patients were used to validate the

SUBMITTER: Lan Z 

PROVIDER: S-EPMC10032006 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature