Sleep duration and timing are prospectively linked with insulin resistance during late adolescence.

ABSTRACT:

Objective

The aim of this study was to evaluate whether short sleep duration or later sleep timing is a risk factor for insulin resistance (IR) in late adolescence.

Methods

Mexico City adolescents enrolled in a longitudinal birth cohort (ELEMENT) took part in two study visits during peri-puberty that occurred approximately 2 years apart. IR was assessed with serum glucose and insulin. Four groups were defined using puberty-specific cut points: no IR over the follow-up period, transition from normal to IR, transition from IR to normal, and IR at both time points. Baseline sleep assessments were measured with 7-day wrist actigraphy. Multinomial logistic regression models were used to evaluate associations between sleep duration and timing with homeostatic model assessment of i

SUBMITTER: Jansen EC 

PROVIDER: S-EPMC10033442 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature