Sex hormones, SHBG and cognitive performance among older Australian women: an observational study.

ABSTRACT:

Objective

This study aims to explore the associations between sex hormones and cognitive performance in older women.

Methods

Associations between sex hormones, sex hormone binding globulin (SHBG) and cognitive performance were examined in women aged at least 70 years, without dementia and not using medications that influence sex hormones. Linear and generalized linear regression models included age, body mass index, education, smoking, alcohol, living circumstances, diabetes, hypertension, depression and impaired renal function.

Results

The included 5511 women had a median (interquartile range) age of 73.9 (71.6-77.6) years. No associations were found for estrone, estradiol, testosterone or dehydroepiandrosterone and cognitive performance. SHBG concentrations above qu

SUBMITTER: Sultana F 

PROVIDER: S-EPMC10033445 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature