Association of macular vessel density and ganglion cell complex thickness with central visual field progression in glaucoma.

ABSTRACT:

Background/aims

To evaluate the association of macular vessel density (VD) and ganglion cell complex (GCC) thickness with 10-2 central visual field (CVF) progression in glaucoma.

Methods

In this retrospective cohort study, patients with glaucoma from Diagnostic Innovation in Glaucoma Study with≥five 10-2 visual field (VF) tests and 3-year follow-up before optical coherence tomography (OCT) and OCT angiography (OCTA) imaging were included. Whole-image GCC thickness (wiGCC) and superficial VD (wiVD) were obtained from 6*6 macula scans. The association of wiVD and wiGCC with past rate of 10-2 VF mean deviation worsening, and with past CVF progression (defined using clustered linear regression criteria) was evaluated using linear mixed models after adjusting for confounders.

SUBMITTER: Wu JH 

PROVIDER: S-EPMC10033463 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature