Endogenous progesterone in unexplained infertility: a systematic review and meta-analysis.

ABSTRACT:

Purpose

To investigate the possibility that altered actions of endogenous progesterone affect receptivity and contribute to unexplained infertility (UI).

Methods

Two authors electronically searched MEDLINE, CINAHL and Embase databases from inception to 6 July 2022 and hand-searched according to Cochrane methodology. We included all published primary research reporting outcomes related to endogenous progesterone in natural cycles in women with UI. Studies were assessed for risk of bias using a modified Newcastle-Ottawa Score or NHLBI Score. We pooled results where appropriate using a random-effects model. Findings were reported as odds ratios or mean differences.

Results

We included 41 studies (n = 4023). No difference was found between the mid-luteal serum progesteron

SUBMITTER: Raperport C 

PROVIDER: S-EPMC10033797 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature