Development and validation of nomograms for predicting survival in differentiated thyroid cancer patients with or without radioiodine therapy

ABSTRACT:

Objective

This study aimed to establish and validate the nomograms for predicting overall survival (OS) probabilities in differentiated thyroid cancer (DTC) patients who received and did not receive radioiodine therapy (RAI), respectively.

Methods

In this study, 11, 099 patients diagnosed with DTC in the Surveillance, Epidemiology, and End Results (SEER) database from 2004 to 2016 were selected. Whether they have RAI, they are divided into RAI (n=6427) and non-RAI (n=4672) groups. They were randomly assigned to either a training cohort (RAI: n=4498, non-RAI: n=3263) or a validation cohort (RAI: n=1929, non-RAI: n=1399) using R software to divide the patients in a 7-to-3 ratio randomly. Variables were selected using a backward stepwise method in a Cox regression model to d

SUBMITTER:  

PROVIDER: S-EPMC10034318 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature