Protective effect and mechanism of Polygonatum kingianum against hypoxia-induced injury.

ABSTRACT:

Background

Hypoxia is an essential cause of fatigue and aging, and is associated with the occurrence and development of many diseases. Polygonatum kingianum (PK) is a deficiency-nourishing Chinese herbal medicine utilized as both medicine and food, and it has long been used to ameliorate human conditions associated with fatigue and aging over 2000 years in China. PK is an important genuine-medicinal-materials cultivated in Yunnan, China, and is used by the Bai, Wa, and Zhuang nationalities as a traditional medicine for enhancing immunity, anti-fatigue, and anti-aging, while the preventive effect of PK on hypoxia-induced injury and the underlying mechanism are indefinite.

Aim of the study

The present study aimed to evaluate the anti-hypoxia efficacy and understand the

SUBMITTER: Li X 

PROVIDER: S-EPMC10034467 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature