Cardiac and cerebral hemodynamics with umbilical cord milking compared with early cord clamping: A randomized cluster crossover trial.

ABSTRACT:

Objective

A large, randomized cluster cross-over trial (N = 1730) comparing intact umbilical cord milking (UCM) to early cord clamping (ECC) in non-vigorous near-term/term newborns demonstrated a reduction in cardiorespiratory interventions at birth and less moderate to severe hypoxic ischemic encephalopathy. We evaluated changes in cerebral tissue oxygenation (StO₂), pulse oximetry (SpO₂), pulse rate and fraction of inspired oxygen (FiO₂) during the first 10 min of life in a subset of infants enrolled in the parent trial.

Study design

Infants enrolled in the Milking in Non-Vigorous Infants trial that had StO₂ monitoring at birth were included in the sub-study conducted at 3 hospitals the US and Canada. A near-infrared spectroscopy

SUBMITTER: Katheria AC 

PROVIDER: S-EPMC10034920 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature