Scandinavian trial of uncomplicated aortic dissection therapy: study protocol for a randomized controlled trial.

ABSTRACT:

Background

Contemporary management of uncomplicated type B aortic dissections (uTBAD) is based on the acuity and various morphological features. Medical therapy is mandatory, while the risks of early thoracic endovascular aortic repair (TEVAR) are balanced against the potential for rupture, complex surgery, and death. Improved aortic morphology following TEVAR is documented, but evidence for improved overall survival is lacking. The costs and impact on quality of life are also needed.

Methods

The trial is a randomized, open-label, superiority clinical trial with parallel assignment of subjects at 23 clinical sites in Denmark, Norway, Sweden, Finland, and Iceland. Eligibility includes patients aged ≥ 18 with uTBAD of < 4 weeks duration. Recruited subjects will be randomized t

SUBMITTER: Rudolph C 

PROVIDER: S-EPMC10035204 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature