GlyLES: Grammar-based Parsing of Glycans from IUPAC-condensed to SMILES.

ABSTRACT: Glycans are important polysaccharides on cellular surfaces that are bound to glycoproteins and glycolipids. These are one of the most common post-translational modifications of proteins in eukaryotic cells. They play important roles in protein folding, cell-cell interactions, and other extracellular processes. Changes in glycan structures may influence the course of different diseases, such as infections or cancer. Glycans are commonly represented using the IUPAC-condensed notation. IUPAC-condensed is a textual representation of glycans operating on the same topological level as the Symbol Nomenclature for Glycans (SNFG) that assigns colored, geometrical shapes to the main monomers. These symbols are then connected in tree-like structures, visualizing the glycan structure on a topological

SUBMITTER: Joeres R 

PROVIDER: S-EPMC10035253 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature