Transcranial direct current stimulation enhances motor learning in Parkinson's disease: a randomized controlled trial.

ABSTRACT: Writing training has shown clinical benefits in Parkinson's disease (PD), albeit with limited retention and insufficient transfer effects. It is still unknown whether anodal transcranial direct current stimulation (atDCS) can boost consolidation in PD and how this interacts with medication. To investigate the effects of training + atDCS versus training + sham stimulation on consolidation of writing skills when ON and OFF medication. Second, to examine the intervention effects on cortical excitability. In this randomized sham-controlled double-blind study, patients underwent writing training (one session) with atDCS (N = 20) or sham (N = 19) over the primary motor cortex. Training was aimed at optimizing amplitude and assessed during online practice, pre- and post-training, after 24-h reten

SUBMITTER: Broeder S 

PROVIDER: S-EPMC10035486 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature