Paired associative stimulation applied to the cortex can increase resting-state functional connectivity: A proof of principle study.

ABSTRACT:

Introduction

There is emerging evidence that high Beta coherence (hBc) between prefrontal and motor corticies, measured with resting-state electroencephalography (rs-EEG), can be an accurate predictor of motor skill learning and stroke recovery. However, it remains unknown whether and how intracortical connectivity may be influenced using neuromodulation. Therefore, a cortico-cortico PAS (ccPAS) paradigm may be used to increase resting-state intracortical connectivity (rs-IC) within a targeted neural circuit.

Purpose

Our purpose is to demonstrate proof of principle that ccPAS can be used to increase rs-IC between a prefrontal and motor cortical region.

Methods

Eleven non-disabled adults were recruited (mean age 26.4, sd 5.6, 5 female). Each participant underwent a dou

SUBMITTER: Hooyman A 

PROVIDER: S-EPMC10035603 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature